Jesse A. Brown, Ph.D.

Individual differences in socioemotional sensitivity are an index of salience network function.
Toller G, Brown J, Sollberger M, Shdo SM, Bouvet L, Sukhanov P, Seeley WW, Miller BL, Rankin KP.
Cortex. 2018 Jun;103:211-223.
http://dx.doi.org/10.1016/j.cortex.2018.02.012

Minimum spanning tree analysis of the human connectome.
van Dellen E, Sommer IE, Bohlken MM, Tewarie P, Draaisma L, Zalesky A, Di Biase M, Brown JA, Douw L, Otte WM, Mandl RCW, Stam CJ.
Hum Brain Mapp. 2018 Jun;39(6):2455-2471.
http://dx.doi.org/10.1002/hbm.24014

The Longitudinal Trajectory of Default Mode Network Connectivity in Healthy Older Adults Varies As a Function of Age and Is Associated with Changes in Episodic Memory and Processing Speed.
Staffaroni AM, Brown JA, Casaletto KB, Elahi FM, Deng J, Neuhaus J, Cobigo Y, Mumford PS, Walters S, Saloner R, Karydas A, Coppola G, Rosen HJ, Miller BL, Seeley WW, Kramer JH.
J Neurosci. 2018 Mar 14;38(11):2809-2817.
http://dx.doi.org/10.1523/JNEUROSCI.3067-17.2018

An 8-week, open-label, dose-finding study of nimodipine for the treatment of progranulin insufficiency from GRN gene mutations.
Sha SJ, Miller ZA, Min SW, Zhou Y, Brown J, Mitic LL, Karydas A, Koestler M, Tsai R, Corbetta-Rastelli C, Lin S, Hare E, Fields S, Fleischmann KE, Powers R, Fitch R, Martens LH, Shamloo M, Fagan AM, Farese RV Jr, Pearlman R, Seeley W, Miller BL, Gan L, Boxer AL.
Alzheimers Dement (N Y). 2017 Sep 12;3(4):507-512.
http://dx.doi.org/10.1016/j.trci.2017.08.002

Clinicopathological correlations in behavioural variant frontotemporal dementia.
Perry DC, Brown JA, Possin KL, Datta S, Trujillo A, Radke A, Karydas A, Kornak J, Sias AC, Rabinovici GD, Gorno-Tempini ML, Boxer AL, De May M, Rankin KP, Sturm VE, Lee SE, Matthews BR, Kao AW, Vossel KA, Tartaglia MC, Miller ZA, Seo SW, Sidhu M, Gaus SE, Nana AL, Vargas JNS, Hwang JL, Ossenkoppele R, Brown AB, Huang EJ, Coppola G, Rosen HJ, Geschwind D, Trojanowski JQ, Grinberg LT, Kramer JH, Miller BL, Seeley WW.
Brain. 2017 Dec 1;140(12):3329-3345.
http://dx.doi.org/10.1093/brain/awx254

Advancing functional dysconnectivity and atrophy in progressive supranuclear palsy.
Brown JA, Hua AY, Trujllo A, Attygalle S, Binney RJ, Spina S, Lee SE, Kramer JH, Miller BL, Rosen HJ, Boxer AL, Seeley WW.
Neuroimage Clin. 2017 Sep 12;16:564-574.
http://dx.doi.org/10.1016/j.nicl.2017.09.008

Suzee E. Lee, Ana C. Sias, Maria Luisa Mandelli, Jesse A. Brown, Alainna B. Brown, Anna M. Khazenzon, Anna A. Vidovszky, Theodore P. Zanto, Anna M. Karydas, Mochtar Pribadi, Deepika Dokuru, Giovanni Coppola, Dan H. Geschwind, Rosa Rademakers, Maria Luisa Gorno-Tempini, Howard J. Rosen, Bruce L. Miller, William W. Seeley.
Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers (2016).
Neuroimage: Clinical
http://dx.doi.org/10.1016/j.nicl.2016.12.006 | PDF

Jennifer S. Yokoyama, Gabe Marx, Jesse A. Brown, Luke W. Bonham, Dan Wang, Giovanni Coppola, William W. Seeley, Howard J. Rosen, Bruce L. Miller, Joel H. Kramer, Dena B. Dubal.
Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging (2016).
Brain Imaging and Behavior
http://dx.doi.org/10.1007/s11682-016-9598-2 | PDF

Maria Luisa Mandelli, Eduard Vilaplana, Jesse A. Brown, H. Isabel Hubbard, Richard J. Binney, Suneth Attygalle, Miguel A. Santos-Santos, Zachary A. Miller, Mikhail Pakvasa, Maya L. Henry, Howard J. Rosen, Roland G. Henry, Gil D. Rabinovici, Bruce L. Miller, William W. Seeley, Maria Luisa Gorno-Tempini.
Healthy brain connectivity predicts atrophy progression in non-fluent variant of primary progressive aphasia (2016).
Brain
http://dx.doi.org/10.1093/brain/aww195 | PDF

Sugeerth Murugesan, Kristofer Bouchard, Jesse A Brown, Bernd Hamann, William W. Seeley, Andrew Trujillo and Gunther H. Weber.
Brain Modulyzer: Interactive Visual Analysis of Functional Brain Connectivity (2016).
IEEE Transactions on Computational Biology and Bioinformatics
http://dx.doi.org/10.1109/TCBB.2016.2564970 | PDF

Neil G. Harris, DR Verley, BA Gutman, PM Thompson, HJ Yeh, Jesse A. Brown.
Disconnection and hyper-connectivity underlie reorganization after TBI: A rodent functional connectomic analysis (2016).
Experimental Neurology
http://dx.doi.org/10.1016/j.expneurol.2015.12.020 | PDF

Jesse A. Brown, John D. Van Horn.
Connected brains and minds – the UMCD repository for brain connectivity matrices (2015).
Neuroimage
http://dx.doi.org/10.1016/j.neuroimage.2015.08.043 | PDF

Jamie Feusner, Teena Moody, Tsz Man Lai, Courtney Sheen, Sahib Khalsa, Jesse A. Brown, Jennifer Levitt, Jeffry Alger Joseph O'Neill.
Brain connectivity and prediction of relapse after cognitive-behavioral therapy in obsessive-compulsive disorder (2015).
Frontiers in Psychiatry
http://dx.doi.org/10.3389/fpsyt.2015.00074 | PDF

Moriah E. Thomason, Jesse A. Brown, Maya T. Dassanayake, Rupal Shastri, Hilary A. Marusak, Edgar Hernandez-Andrade, Lami Yeo, Swati Mody, Susan Berman, Sonia S. Hassan, Roberto Romero.
Intrinsic functional brain architecture derived from graph theoretical analysis in the human fetus (2014).
PLoS ONE
http://dx.doi.org/10.1371/journal.pone.0094423 | PDF

Ariana Anderson, Pamela K. Douglas, Wesley T. Kerr, Virginia S. Haynes, Alan L. Yuille, Jianwen Xie, Ying Nian Wu, Jesse A. Brown, Mark S. Cohen.
Non-negative matrix factorization of multimodal MRI, fMRI and phenotypic data reveals differential changes in default mode subnetworks in ADHD (2013).
Neuroimage
http://dx.doi.org/10.1016/j.neuroimage.2013.12.015 | PDF

Alison Burggren, Jesse A. Brown.
Imaging markers of structural and functional brain changes that precede cognitive symptoms in risk for Alzheimer’s disease (2013).
Brain Imaging and Behavior
http://dx.doi.org/10.1007/s11682-013-9278-4 | PDF

Susan Y. Bookheimer, Brian A. Renner, Arne Ekstrom, Zhaoping Li, Sussane M. Henning, Jesse A. Brown, Mike Jones, Teena Moody, Gary W. Small.
Pomegranate juice augments memory and FMRI activity in middle-aged and older adults with mild memory complaints (2013).
Evid Based Complement Alternat Med
http://dx.doi.org/10.1155/2013/946298 | PDF

Donatello Arienzo, Alex Leow, Jesse A. Brown, Liang Zhan, Johnson GadElkarim, Sarit Hovav, Jamie D. Feusner.
Abnormal brain network organization in body dysmorphic disorder (2013).
Neuropsychopharmacology
http://dx.doi.org/10.1038/npp.2013.18 | PDF

Jesse A. Brown, Jeffrey D. Rudie, Anita Bandrowski, John D. Van Horn, Susan Y. Bookheimer.
The UCLA Multimodal Connectivity Database: A web-based platform for connectivity matrix sharing and complex network analysis (2012).
Frontiers in Neuroinformatics
http://dx.doi.org/10.3389/fninf.2012.00028 | PDF

JD Rudie, Jesse A. Brown, D Beck-Pancer, LM Hernandez, EL Dennis, PM Thompson, SY Bookheimer, M Dapretto.
Altered Functional and Structural Brain Network Organization in Autism (2012).
Neuroimage: Clinical
http://dx.doi.org/10.1016/j.nicl.2012.11.006 | PDF

J.D. Rudie, L.M. Hernandez, Jesse A. Brown, D. Beck-Pancer, N.L. Colich, P. Gorrindo, P.M. Thompson, D.H. Geschwind, S.Y. Bookheimer, P. Levitt, and M. Dapretto.
Autism-Associated Promoter Variant in MET Impacts Functional and Structural Brain Networks (2012).
Neuron
http://dx.doi.org/10.1016/j.neuron.2012.07.010 | PDF

John B. Colby, Jeffrey D. Rudie, Jesse A. Brown, Pamela K. Douglas, Mark S. Cohen, Zarrar Shehzad.
Insights into multimodal imaging classification of ADHD (2012).
Frontiers in Systems Neuroscience
http://dx.doi.org/10.3389/fnsys.2012.00059 | PDF

Emily L. Dennis, Neda Jahanshad, Jeffrey D. Rudie, Jesse A. Brown, Kori Johnson, Katie L. McMahon, Greig I. de Zubicaray, Grant Montgomery, Nicholas G. Martin, Margaret J. Wright, Susan Y. Bookheimer, Mirella Dapretto, Arthur W. Toga, Paul M. Thompson.
Abnormal Structural Brain Connectivity in Healthy Carriers of the Autism Risk Gene, CNTNAP2 (2012).
Brain Connectivity
http://dx.doi.org/10.1089/brain.2011.0064 | PDF

Jesse A. Brown, Kevin H. Terashima, Alison C. Burggren, Linda M. Ercoli, Karen J. Miller, Gary W. Small, Susan Y. Bookheimer.
Brain network local interconnectivity loss in aging APOE-4 allele carriers (2011).
Proc Natl Acad Sci
http://dx.doi.org/10.1073/pnas.1109038108 | PDF

Donix M, Ercoli LM, Siddarth P, Jesse A. Brown, Martin-Harris L, Burggren AC, Miller KJ, Small GW, Bookheimer SY.
Influence of Alzheimer Disease Family History and Genetic Risk on Cognitive Performance in Healthy Middle-Aged and Older People (2011).
Am J Geriatr Psychiatry
http://dx.doi.org/10.1097/JGP.0b013e3182107e6a | PDF

Danielle S. Bassett, Jesse A. Brown, Vibhas Deshpande, Jean M. Carlson, Scott T. Grafton.
Conserved and variable architecture of human white matter connectivity (2011).
Neuroimage
http://dx.doi.org/10.1016/j.neuroimage.2010.09.006 | PDF

Natcha Opalka, Jesse A. Brown, William J. Lane, Kelly-Anne F. Twist, Robert Landick, Francisco J. Asturias, Seth A. Darst.
Complete Structural Model of Escherichia coli RNA Polymerase from a Hybrid Approach (2010).
PLoS Biology
http://dx.doi.org/10.1371/journal.pbio.1000483 | PDF

Yuchiro Takagi, Guillermo Calero, Hirofumi Komori, Jesse A. Brown, Andres Ehrensberger, Andy Hudmon, Francisco J. Asturias, Roger D. Kornberg.
Head Module Control of Mediator Interactions (2006).
Molecular Cell
http://dx.doi.org/10.1016/j.molcel.2006.06.007 | PDF

Book Chapters
Jesse A. Brown and William W. Seeley.
Progressive Supranuclear Palsy and Related Parkinsonian Disorders.
Genomics, Circuits, and Pathways for the Clinical Neuroscientist.
http://dx.doi.org/10.1016/B978-0-12-800105-9.00018-4 | PDF

Dissertation
Jesse A. Brown
Multimodality MRI-based Brain Network Analysis: Applications to Genetic Risk for Alzheimer’s Disease
http://search.proquest.com/docview/1345970670